DuPont & University of Virginia Study Demonstrates Probiotics Support Respiratory Immune Function

HOWARU® Protect Adult (Bl-04™) is one of the best documented probiotics for immune health in the world, and we are proud to be able to deliver an efficacious and stable probiotic to the industry so consumers can benefit.

DuPont Nutrition & Health (DuPont) announced today that a study published in Beneficial Microbes and sponsored by DuPont and the University of Virginia demonstrated the role of probiotic supplementation to maintain healthy respiratory immune function. The results of a randomized, double-blind, placebo controlled study investigating the effect probiotics had on the immune response in healthy, rhinovirus-challenged adult human subjects suggest that ingestion of Bl-04™ at a dose of 2 billion cfu per day has an effect on the inflammatory response to rhinovirus infection(1). The common cold is one of the most prevalent diseases globally and is typically caused by rhinovirus infection.

A specific probiotic strain Bifidobacterium lactis Bl-04™ (Bl-04™), available only from DuPont, was consumed by participants for one month, and innate immune response and presence of rhinovirus in the nostrils was investigated. The virus and the immune markers were analyzed from nasal washes, collected before and after Bl-04™ supplementation and for 5 days after the introduction of the rhinovirus challenge. Compared to placebo, the probiotic supplement, commercially available HOWARU® Protect Adult, had an effect on the presence of the virus in the nostrils, demonstrated by a decreased amount of rhinovirus in nasal washes during infection and a lower proportion of study participants with rhinovirus detected in nasal washes.

“The effects observed in this short-term, well-controlled study were modest and may only…

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